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Medical Entrepreneurs II (ME2) was a medical device company based in Scotts Valley, California, that specialized in the development of prosthetic heart valves and transcatheter delivery systems. Founded in 2007 by Geoff Dillon and Michael Sumner Estes, the company was recognized as the first to apply a "generic" business model to Class III medical devices, aiming to replicate "gold standard" heart valves at a lower cost. Its portfolio included innovative designs for aortic, mitral, and tricuspid valve replacements, as well as expandable sheaths for endovascular delivery. The company's technology and intellectual property were acquired by St. Jude Medical (now Abbott), which integrated ME2's cardiology innovations into its structural heart portfolio.
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