Company intelligence / Profile preview

Metagenomi

Emeryville, California, United Statesmetagenomi.co ↗
Ownership
Public · MGX
Employees
~202
Development stage
Preclinical
01

Overview

Metagenomi has a lead program for Hemophilia A (MGX-001) that demonstrated sustained FVIII activity in NHP studies for more than 16 months. The company has also achieved in vivo proof-of-concept in rodents for three secreted protein targets and four cardiometabolic programs in collaboration with Ionis, including 95% protein knockdown in spontaneous hypertensive rats.

Therapeutic areas
HematologyEndocrinologyRare DiseasesCardiovascular
Modalities
Gene editingBase editorsRNA-mediated integrationDNA-mediated integrationPrime editing systemsCRISPR-associated transposases (CAST)
Industry
Biotech
02

Drug pipeline

5 assets

MGX-001

Preclinical

4 more assets in the full pipeline.

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03

Partnerships

Ionis PharmaceuticalsAffini-T TherapeuticsModerna (terminated May 2024)
04

Financials

Market cap
$43.7M
Total revenue
$-257K
Enterprise value
$-39.3M

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