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MetaStem Therapeutics, a University of British Columbia startup, collaborates with academic and industry partners to develop next-generation antibody drug conjugate therapies targeting podocalyxin for the treatment of metastatic cancers. Their lead program aims to optimize an ADC for ovarian and pancreatic cancers, with the goal of rapid clinical translation. The company has not yet reported human clinical results but has received significant grant funding and support for preclinical optimization.
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