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MetroBiotech’s lead compound, MIB-626 (crystallized NMN), increases NAD+ levels in humans and is in Phase 2 trials for COVID-19, kidney injury, and rare mitochondrial diseases. Early clinical results show pharmacological activity and no dose-limiting toxicities for MIB-725 in Phase 1a; robust preclinical efficacy in diseases of aging. MIB-626 demonstrated NAD+ increases in human blood within one week
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