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MGX

Emeryville, California, USA
Ownership
Private
Employees
~200
Development stage
Other
01

Overview

Metagenomi is a precision genetic medicines company developing a proprietary portfolio of next-generation gene editing tools. By leveraging a vast database of metagenomic data, the company identifies and optimizes novel CRISPR-based systems, including base editors and RNA-mediated integration systems. Their platform aims to overcome the limitations of first-generation gene editing technologies, such as size constraints and PAM requirements, to treat a wide range of genetic diseases. The company's pipeline includes programs for metabolic, cardiovascular, and neuromuscular disorders, supported by strategic collaborations with industry leaders like Ionis Pharmaceuticals.

Therapeutic areas
HematologyCardiovascularRare Diseases
Modalities
Gene therapyCRISPR-based therapyBase editingRNA-mediated integration
Industry
Biotech
02

Partnerships

Ionis PharmaceuticalsAffini-T TherapeuticsModerna

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