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Ohr Pharmaceutical developed squalamine eye drops for wet AMD and other retinal diseases but failed to meet primary endpoints in pivotal trials. The company merged with NeuBase Therapeutics in 2019 to focus on rare genetic diseases using a novel peptide-nucleic acid antisense platform targeting severe neurological disorders such as Huntington's disease and myotonic dystrophy. The merged entity planned IND filings starting in 2020.
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