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Lorundrostat, a highly selective aldosterone synthase inhibitor, has demonstrated statistically significant and clinically meaningful reductions in blood pressure in multiple clinical trials. Positive topline results were reported from both the pivotal Launch-HTN Phase 3 and Advance-HTN Phase 2 trials for uncontrolled or resistant hypertension. The drug showed a favorable safety and tolerability profile across studies, supporting its potential regulatory approval and commercial value[7].
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