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Minghui is a clinical-stage biotech with a focus on oncology and immunology, advancing multiple innovative antibody-drug conjugates, bispecific antibodies, and JAK inhibitors. Recent clinical results for MHB039A (PD-1 x VEGF bispecific) show promising antitumor activity in heavily pretreated solid tumor patients, especially non-small cell lung cancer (NSCLC). MHB088C (B7-H3 ADC) has demonstrated robust efficacy and safety in >300 patients, with ongoing Phase III trials in small cell lung cancer (SCLC).
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