Company intelligence / Profile preview

Minicircle

Roatan / Próspera, Islas de la Bahía, Hondurasminicircle.io ↗
Ownership
Private
Development stage
Other
01

Overview

Minicircle has developed a platform for delivering genes via non-integrating DNA minicircles. Their lead program delivers follistatin to increase muscle mass and reduce inflammation. Early self-administration and initial patient results have been positive. The company operates clinics outside the US due to regulatory constraints and has begun Phase 1 trials in Honduras/Próspera. They plan to seek FDA approval for US clinical use soon.

Therapeutic areas
NephrologyMetabolic DisordersImmunologyRare DiseasesGastroenterologyNeurologyInfectious Diseases
Modalities
Gene therapy using DNA minicircles (non-integrating plasmid-based gene delivery)
Industry
Biotech
02

Drug pipeline

4 assets

Klotho (Minicircle)

Preclinical

3 more assets in the full pipeline.

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03

Partnerships

No major pharma partnerships disclosed; some collaborations with clinics such as GARM Clinic in Roatan/Hondurasearly-stage investors from longevity space and Silicon Valley private investors

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