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Lead candidates MTX325 (USP30 inhibitor for Parkinson’s Disease, Phase II) and MTX652 (USP30 inhibitor for Heart Failure/HFpEF, Phase II). Several USP30 inhibitor programs in clinic or approaching development. Recent FDA approval for Phase II of MTX652 in Acute Kidney Injury and MHRA CTA for MTX325 in Parkinson’s.[1][3][4]
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