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Milestone Pharmaceuticals received FDA approval of CARDAMYST (etripamil) in December 2025 for paroxysmal supraventricular tachycardia, marking its transition to commercial-stage operations. Etripamil demonstrated efficacy in Phase 3 trials (RAPID and NODE-301), significantly increasing conversion to sinus rhythm compared to placebo. The product is also in Phase 2 development for atrial fibrillation with rapid ventricular rate.[1][3][4]
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