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Miyarisan Pharmaceutical Co., Ltd.

Ownership: Private
Employees: ~398
Development stage: Commercial

Overview

Miyarisan Pharmaceutical is a Japanese pharmaceutical company specializing in live biotherapeutics based on Clostridium butyricum MIYAIRI strains. Their flagship product is approved and marketed in Japan for GI indications and has been approved as a novel food/probiotic in the EU. In partnership with Osel Inc. and City of Hope, CBM588 is being clinically evaluated as an adjunct to checkpoint inhibitor therapy for metastatic renal cell carcinoma; early results show improved progression-free survival compared to standard of care alone.[6][8][10] The company also manufactures OTC probiotics and animal feed additives.

Therapeutic areas: GastroenterologyDermatologyOncologyInfectious Diseases
Modalities: Live biotherapeutic products (probiotics, specifically Clostridium butyricum MIYAIRI strains)Small molecules
Industry: Biotech

Drug pipeline

4 assets

clostridium butyricum

3 more assets in the full pipeline.

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Partnerships

Osel Inc.: Licensing partner for CBM588 clinical development outside Japan[6][10]CHAIN Biotechnology Ltd.: Investment/collaboration on engineered microbiome therapeutics using CADD system[5]Huvepharma & Ardol BV Europe partnerships related to animal feed additive exports/imports [3]

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