Clinical trials
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The lead intranasal COVID‑19 vaccine candidate has demonstrated safety and tolerability in ascending dose cohorts in a Phase I trial and elicited strong mucosal and systemic neutralizing antibody responses as well as a Th1-skewed T cell response against the SARS-CoV‑2 spike protein when given as a boost to subjects previously vaccinated with mRNA vaccines. Preclinical data support broad application of the SC-AdVax platform to multiple infectious diseases.
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