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Moderna pioneered the use of messenger RNA as a therapeutic modality. Its COVID‑19 vaccine ("Spikevax") was among the first to receive global approval. The company has since expanded its commercial portfolio to include an RSV vaccine ("mRESVIA") and continues to advance a broad pipeline across infectious diseases, oncology, rare diseases, and more[1][2][3][5].
As of mid‑2025, Moderna has over 45 development programs with at least three commercial products. Clinical results for its vaccines have shown high efficacy rates—over 90% for COVID‑19—and strong safety profiles[3][7].
Notably, its personalized cancer vaccine candidate developed with Merck received FDA breakthrough status in early 2023[5].
Revenue peaked during the pandemic but remains substantial due to ongoing product sales and new launches[6].
Pipeline breadth: ~45 development programs; ~36 ongoing clinical trials as of June 2025[3].
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