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Modus Therapeutics is in Phase II clinical trials with its lead compound sevuparin, a heparinoid developed for sepsis, severe inflammation, sickle cell anemia, and chronic kidney disease with anemia. Sevuparin has shown a favorable safety profile and is distinguished by its low anticoagulant activity, enabling higher dosing than standard heparinoids. The ongoing Phase II study in chronic kidney disease with anemia is supported by recent funding and expected to complete by the end of 2026.
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