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MoonLake’s lead asset, sonelokimab, is a novel nanobody-based inhibitor of IL‑17A and IL‑17F. It has demonstrated promising efficacy in phase 2 trials for hidradenitis suppurativa and psoriatic arthritis. The company is preparing to launch phase 3 clinical trials in these indications. Sonelokimab’s mechanism allows it to target multiple forms of IL‑17 dimers implicated in inflammatory diseases, potentially offering advantages over traditional antibodies.[1][4][5][6]
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