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Mosaic Biomedicals developed MSC-1, a first-in-class monoclonal antibody targeting leukemia inhibitory factor (LIF) to inhibit tumor progression and cancer stem cells in solid tumors; following its merger with Northern Biologics and option deal with Celgene, MSC-1 advanced into multi-center Phase 1 clinical trials in Europe and the United States beginning in 2017.[2][3]
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