MRC Holland

MRC Holland is a leading biotechnology company specializing in the development and manufacture of molecular diagnostic assays. The company is best known for inventing Multiplex Ligation-dependent Probe Amplification (MLPA), a gold-standard technology for detecting copy number variations (CNVs) in genomic DNA. Their product portfolio includes over 400 SALSA MLPA assays targeting various hereditary disorders and oncology indications, such as spinal muscular atrophy and BRCA-related cancers. MRC Holland also offers digitalMLPA, which combines traditional MLPA with next-generation sequencing for high-throughput analysis. Headquartered in Amsterdam, the company serves clinical and research laboratories worldwide.