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MSI Methylation Sciences

Surrey/Burnaby/Vancouver*, British Columbia, Canadastartupportugal.dealroom.co ↗

Ownership: Private
Employees: ~75
Development stage: Phase 2

Overview

MSI’s lead candidate, MSI-195 (a proprietary formulation of SAMe), was evaluated in a Phase 2 clinical trial as an add-on therapy for patients with Major Depressive Disorder who had inadequate response to current antidepressants. The study did not meet its primary endpoint versus placebo; however, post-hoc analyses suggested some beneficial treatment differences and the drug was well tolerated. A Phase 1 pharmacokinetic and safety study comparing MSI-195 to a commercial SAMe product has also been completed

Therapeutic areas: PsychiatryNeurology
Modalities: small molecules (notably S-Adenosyl-L-Methionine/SAMe-based formulations)
Industry: Biotech

Drug pipeline

1 asset

MSI-195

Unknown

Partnerships

Quark Venture Inc. invested $30 million USD for continued development of MSI‑195 but later defaulted on further payments leading to legal proceedings; no major pharma partnerships disclosed

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