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Nakima Therapeutics is a stealth-mode biotechnology company focused on developing novel small molecule inhibitors for the treatment of cancer. The company's primary research centers on targeting Nicotinamide phosphoribosyltransferase (NAMPT), a key enzyme in the NAD+ salvage pathway that is frequently overexpressed in various malignancies. By inhibiting NAMPT, Nakima aims to disrupt the metabolic processes of cancer cells, leading to NAD+ depletion and subsequent cell death. Founded and backed by Westlake Village BioPartners, the company is currently advancing its lead programs through pre-clinical development. The company is headquartered in Thousand Oaks, California, and operates within the precision oncology space.
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