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Natural Pharma International (NPI) is a Swiss-based biopharmaceutical company dedicated to the development of innovative therapies for rare neurodegenerative and ophthalmic diseases. The company's lead candidate, NPI-001, is a high-purity pharmaceutical formulation of tauroursodeoxycholic acid (TUDCA) aimed at treating Retinitis Pigmentosa and Usher Syndrome. NPI-001 functions as a chemical chaperone that reduces endoplasmic reticulum stress and prevents apoptosis in photoreceptor cells, thereby preserving visual function. The company has received Orphan Drug Designation for NPI-001 from both the U.S. FDA and the European Medicines Agency. NPI focuses on bridging the gap between natural substances and modern pharmaceutical standards through rigorous R&D and clinical validation.
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