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Nereus Pharmaceuticals specialized in the discovery and clinical development of marine-derived small molecule drug candidates, particularly for oncology. As of its acquisition in 2012, its lead compounds (plinabulin/NPI-2358 and salinosporamide A/NPI-0052) had entered Phase I trials for various cancers, and multiple preclinical programs were reported for oncology, infectious disease, and inflammation.[1][2][4]
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