Nerium

Nerium Biotechnology was a biotechnology company focused on oleander-based therapeutics and skincare products derived from proprietary plant extracts. Its lead oncology asset was Anvirzel, and its development portfolio also referenced PBI-05204, HIviral, HEP-viral, and NeriumAD. The company positioned its technology around extracts of Nerium oleander and related formulations for proliferative diseases, viral infections, and topical age-defying skincare. Publicly available sources indicate the company was headquartered in San Antonio, Texas, registered with the SEC, and later became inactive or out of business. Based on published descriptions of PBI-05204 and related oleander extracts, the most advanced disclosed programs appear to have reached Phase 2 in solid tumors.