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NeXstar Pharmaceuticals

Boulder, CO, United Statesgilead.com ↗

Ownership: Private
Employees: ~500
Development stage: Commercial

Overview

At the time of its acquisition by Gilead Sciences in mid‑1999, NeXstar had two commercial products—AmBisome® for serious fungal infections and DaunoXome® for Kaposi’s Sarcoma—and a robust pipeline including MiKasome®, NX1838 for macular degeneration, NX211 for oncology indications, as well as oligonucleotide therapeutics. Its clinical programs spanned from preclinical through Phase III trials.[1][5][6]

Therapeutic areas: OphthalmologyOncologyImmunologyInfectious Diseases
Modalities: Liposomal drug formulations (liposomes)Small molecules (e.g., daunorubicin citrate, amphotericin B)Oligonucleotides[9]
Industry: Biotech

Drug pipeline

6 assets

amphotericin B

Commercial

Indications: Fungal infections

5 more assets in the full pipeline.

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Partnerships

Notable licensing/collaboration with Glaxo Wellcome on lurtotecan liposomal development; partnerships with academic centers such as Erasmus MC noted in trial sponsorships.[7][10]

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