Company intelligence / Profile preview

NGM Biopharmaceuticals

South San Francisco, California, United Statesngmbio.com ↗
Ownership
Public · NGM
Employees
~129
Development stage
Phase 2
01

Overview

NGM Bio has a robust pipeline of biologics primarily focused on monoclonal antibodies targeting novel pathways in oncology and metabolic/liver diseases. Recent clinical results include:

  • Ongoing Phase 1/2 trial of NGM707 + pembrolizumab in advanced/metastatic solid tumors.
  • Completed enrollment for Phase 1b trials of NGM831 + pembrolizumab and NGM438 + pembrolizumab in solid tumors.
  • Completed a Phase 2 trial of NGM120 for metastatic pancreatic cancer; no clear efficacy signal detected—oncology development paused. However, development continues for hyperemesis gravidarum with ongoing discussions with the FDA. Aldafermin remains under consideration for PSC pending further regulatory guidance and capital availability.
Therapeutic areas
Women's HealthOncologyGastroenterologyEndocrinology
Modalities
AntibodyMonoclonal antibodyProtein
Industry
Biotech
02

Drug pipeline

13 assets

aldafermin

3

12 more assets in the full pipeline.

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03

Partnerships

Merck & Co.: Strategic R&D collaboration including licensing option rights to certain assets such as MK‑3655.KdT Ventures agreement regarding the FGFR agonist program.
04

Financials

Market cap
$128.5M
Total revenue
$165K
Enterprise value
$-18.7M

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