Company intelligence / Profile preview

NLS Pharmaceutics AG

Zurich, Zurich, Switzerlandnlspharma.com ↗
Ownership
Public · NLSP
Employees
~45
Development stage
Other
01

Overview

NLS Pharmaceutics AG develops therapies targeting rare and complex central nervous system disorders. Its lead asset, Quilience® (mazindol extended-release), has advanced to Phase III trials for narcolepsy. The company’s pipeline includes additional small molecule candidates and a newly licensed dual orexin receptor agonist platform (“DOXA”), which targets both symptomatic relief and disease modification in sleep-wake and neurodegenerative disorders. Recent preclinical data are promising, especially regarding the novel mechanism involving both orexin receptors and cathepsins. The company recently announced plans to merge with Kadimastem Ltd., combining cell therapy expertise with its CNS drug portfolio.

Therapeutic areas
NeurologyInfectious Diseases
Modalities
Small molecules (e.g., Mazindol ER/Quilience, AEX series)Dual orexin receptor agonists
Industry
Biotech
02

Drug pipeline

11 assets

Mazindol ER

3

10 more assets in the full pipeline.

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03

Partnerships

Jazz PharmaceuticalsUniversity Hospital ZurichStanford University Sleep Research CenterExclusive global license from Aexon Labs Inc. for DOXA platform
04

Financials

Market cap
$919.6K
Total revenue
$0
Enterprise value
$-2.2M

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