No Resistance

NoResistance is a French biotechnology company focused on addressing the global crisis of antimicrobial resistance (AMR). A spin-off from the Institut Pasteur, the company develops innovative small molecule adjuvants designed to restore the efficacy of existing antibiotics against multidrug-resistant bacteria. Their technology targets specific bacterial mechanisms that confer resistance, effectively re-sensitizing pathogens to standard-of-care treatments. By extending the life of current antibiotics, NoResistance aims to provide new solutions for hard-to-treat infections without the immediate need for entirely new classes of antimicrobial agents. The company's approach focuses on high-impact clinical needs where resistance has rendered traditional therapies ineffective.