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Nocion Therapeutics

Watertown / Waltham*, Massachusetts, United States
Ownership
Private
Development stage
Phase 2
01

Overview

The lead program Taplucainium Dry Powder for Inhalation has advanced into a Phase 2b study in patients with chronic cough. The company’s approach selectively silences activated sensory neurons implicated in conditions like chronic cough and pain while minimizing off-target effects such as numbness or paralysis. Early results suggest potential benefits over standard sodium channel blockers and P2X3 antagonists.

Therapeutic areas
NeurologyPulmonologyDermatologyImmunology
Modalities
Small molecules (specifically, permanently charged sodium channel blockers called "nocions")
Industry
Biotech
02

Drug pipeline

2 assets

taplucainium chloride

2

1 more asset in the full pipeline.

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03

Partnerships

Harvard University/Boston Children’s Hospital – exclusive license to foundational intellectual property from these institutionsNo major pharma partnerships publicly disclosed.

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