Noesis ChemoInformatics

Noesis ChemoInformatics was a Cyprus-based biotechnology company specializing in computational drug discovery and chemoinformatics. Founded in 2006, the company focused on developing advanced algorithms for de novo drug design, most notably the Multiobjective Evolutionary Graph Algorithm (MEGA). This platform allowed for the simultaneous optimization of multiple chemical and biological properties, such as potency, selectivity, and ADMET profiles, to identify promising drug candidates. The company's research, often conducted in collaboration with the University of Cyprus and other academic institutions, targeted various therapeutic areas including HIV and GPCR-related disorders. Although the company is currently listed as dissolved, its technological contributions to multiobjective optimization in drug discovery remain influential in the field of computational chemistry.