Company intelligence / Profile preview
Nona Biosciences
Cambridge, Massachusetts, United Statesnonabio.com ↗
- Ownership
- Private
- Development stage
- Other
01
Overview
Nona Biosciences has demonstrated robust antibody engineering capabilities with proprietary transgenic mouse platforms. Their technologies have enabled the generation of novel therapeutic candidates—such as the mesothelin-targeting ADC developed with Pfizer—which have shown promising preclinical results presented at AACR in April 2025. The company’s focus remains on accelerating antibody drug discovery from target validation through IND-enabling studies using both traditional wet-lab methods and advanced AI-driven approaches.
- Therapeutic areas
- OncologyMetabolic DisordersNeurology
- Modalities
- Fully human monoclonal antibodies (H2L2 format)Heavy chain only antibodies (HCAb format)Single domain antibodies / VH domainsBispecific/multispecific antibodiesCAR-T and cell therapiesADCs (antibody-drug conjugates)mRNA-based modalities
- Industry
- Biotech
02
Drug pipeline
1 asset03
Partnerships
Pfizer — co-development of mesothelin-targeting ADC PF‑08052666/SGN-MesoC2/HBM9033 [preclinically validated in April 2025].Evive Biotech — collaboration for accelerated antibody discovery.OverT Bio — strategic partnership for next-generation cell therapies targeting solid tumors using HCAb technology.
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