Norian

Norian Corporation is a medical technology company specializing in the development of injectable calcium phosphate bone cements for orthopedic and craniofacial applications. The company is best known for its Norian SRS (Skeletal Repair System), a biocompatible material that chemically transforms into a carbonated apatite similar to natural bone mineral. These products are designed to provide immediate structural support and are gradually remodeled and replaced by the patient's own bone over time. Originally founded in 1987, Norian was acquired by Synthes in 1999 and subsequently became part of DePuy Synthes following Johnson & Johnson's acquisition of Synthes. The technology represents a significant advancement in biomaterials, offering an alternative to traditional bone grafts and metallic fixation in specific clinical scenarios. Despite its clinical success, the company faced significant legal challenges in the 2010s regarding the off-label use of its products in spinal surgeries.