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Noxilizer has commercialized an ultra-low temperature nitrogen dioxide gas sterilization process that operates at 10–30°C. This method offers advantages over traditional methods such as ethylene oxide or gamma irradiation, including minimal residuals, short cycle times (6–12 hours), and compatibility with sensitive products like pre-filled syringes and combination drug-device products. The technology is FDA-cleared for certain applications and used by leading global pharma, biotech, and medical device companies.
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