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Nuvation Bio recently received FDA approval for IBTROZI™ (taletrectinib) as a next-generation oral treatment for adult patients with locally advanced or metastatic ROS1-positive non-small cell lung cancer. The pivotal TRUST program demonstrated high response rates and durable benefit including intracranial activity. Other pipeline programs include safusidenib in phase 2 trials targeting mIDH1-mutant glioma, innovative drug-drug conjugates such as NUV‑1511, and the BD2-selective BET inhibitor NUV‑868.
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