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NurExone Biologic
Toronto, Ontario, Canada
- Ownership
- Private
- Development stage
- Other
01
Overview
The company is developing an off-the-shelf, non-invasive intranasal exosome therapy loaded with PTEN siRNA for reversal or reduction of paralysis following spinal cord injury. The technology has shown significant functional recovery, motor and sensory improvement, and faster urinary reflex restoration in preclinical rat models with complete spinal cord lesion, and the company is working toward a Pre-IND package with regulatory agencies.[2]
- Therapeutic areas
- Neurology
- Modalities
- Exosome-based therapyRNA therapySmall interfering RNA
- Industry
- Biotech
02
Partnerships
Technion – Israel Institute of Technology (exclusive worldwide license for exosome-based spinal cord injury technology and exosome manufacturing process)[2][3]Tel Aviv University (exclusive worldwide license for the spinal cord injury technology)[2][3]denovoMATRIX GmbH (letter of intent for international strategic collaboration towards large-scale exosome production)[2]Nanometrix Ltd. (letter of intent for research collaboration for exosome and cargo molecular profiling)[2]Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (material transfer agreement)[2]
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