Company intelligence / Profile preview

Octagon Therapeutics

Providence, Rhode Island, United Statesoctagontherapeutics.com ↗
Ownership
Private
Development stage
Preclinical
01

Overview

Octagon Therapeutics was a biotech company focused on developing novel medicines for autoimmune and inflammatory diseases by restoring the function of immune checkpoints using glycoproteome insights. The company deprioritized its lead B cell immunomodulator program due to unresolved biology questions and ultimately decided to wind down operations in April 2025. Its most advanced asset was preclinical.

Therapeutic areas
ImmunologyCardiovascular
Modalities
Small molecules (inferred from drug development focus and typical approaches for immune checkpoint modulation)
Industry
Biotech
02

Drug pipeline

4 assets

OCT-50

Preclinical

3 more assets in the full pipeline.

03

Partnerships

Novo Nordisk – research alliance formed in 2022, including participation in Novo’s Co-Creation Greenhouse accelerator program focused on cardiometabolic disease targets.

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