OGRIS Pharma

OGRIS Pharma was a biotechnology company based in Vienna, Austria, that specialized in the development of non-viral gene delivery systems. The company's core technology focused on shielded polyplexes, which are nanoparticle-based carriers designed to protect nucleic acids from degradation and minimize non-specific interactions in the bloodstream. These delivery systems were often functionalized with targeting ligands, such as Epidermal Growth Factor (EGF), to direct therapeutic genes specifically to tumor cells. The company primarily targeted oncology indications, including bladder and ovarian cancers, utilizing its proprietary polymer-based delivery platform to enhance the efficacy and safety of gene-based therapeutics.