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OncoBayes is a privately held, clinical-stage pharmaceutical company based in London, UK, focused on developing innovative oncology therapies to address major unmet medical needs. The company's lead program, OB-001, is a once-daily oral tablet designed as a highly selective inhibitor of key efflux pumps, P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP). By inhibiting these pumps, OB-001 aims to overcome antibody-drug conjugate (ADC) resistance and enhance the brain penetration of tyrosine kinase inhibitors (TKIs) like osimertinib. OncoBayes is preparing to advance OB-001 into clinical trials to generate proof-of-concept data in combination with standard-of-care cancer therapies.
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