Oncology Information Service

Oncology Information Service (OIS) is a specialized provider of real-world data (RWD) and health economics and outcomes research (HEOR) services for the European oncology market. Founded in 1993 and headquartered in Freiburg, Germany, the company maintains the "Therapie Monitor" database, which offers longitudinal, regulatory-grade clinical insights into patient characteristics, treatment patterns, and outcomes across more than 15 cancer types. OIS and its Swiss subsidiary, Cancer Data Net (CDN), provide consultative and operational services in epidemiology, health technology assessment (HTA), and the development of synthetic control arms for clinical trials. In October 2022, OIS was acquired by TriNetX, a global health research network, to expand its European footprint and enhance its ability to provide high-quality oncology data for regulatory decision-making by agencies such as the FDA and EMA. The company's expertise includes the collection of retrospective data from medical charts and the application of machine learning models for statistical analysis of real-world evidence.