Onyx Technology

Onyx Technology is a U.S.-based healthcare interoperability software company focused on FHIR-based data exchange and regulatory compliance for payers, providers, health information exchanges, and government customers. The company commercializes OnyxOS, a cloud-based interoperability platform built on Microsoft Azure that supports CMS and ONC data-sharing requirements, including patient access, payer-to-payer exchange, provider access, and electronic prior authorization workflows. Onyx traces its roots to the team that built CMS Blue Button 2.0 and positions that experience as a core differentiator in payer interoperability. The company appears to operate as an active commercial healthtech business rather than a therapeutics developer, so it does not have a traditional drug pipeline. In January 2026, Onyx announced the acquisition of InteropX to expand execution capabilities around payer interoperability and prior authorization.