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Open Innovation Partners, Inc. is a Tokyo-based biotech company focused on developing antibody-drug conjugates targeting c-Met for solid tumors. Its lead asset, TR1801-ADC, is an anti-c-Met antibody-drug conjugate currently in Phase 1 clinical trials for solid tumors. Preclinical data show high potency and activity against c-Met amplified and non-amplified cancers, including overcoming gemcitabine resistance in pancreatic cancer
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