Company intelligence / Profile preview
Opthea Limited
Melbourne, Victoria, Australiaopthea.com ↗
- Ownership
- Public · OPT
- Development stage
- Phase 3
01
Overview
Opthea Limited is advancing sozinibercept (formerly OPT‑302), a novel biologic targeting VEGF-C and VEGF-D, in two pivotal Phase 3 trials for wet AMD. In Phase 2b studies with ranibizumab, sozinibercept demonstrated superior visual outcomes compared to standard-of-care alone. The ongoing COAST and ShORe Phase 3 trials are fully enrolled with topline results expected in Q2 and mid‑2025 respectively. Sozinibercept could become the first new therapy in two decades to deliver improved vision outcomes for wet AMD patients when used alongside anti–VEGF-A therapies.
- Therapeutic areas
- Ophthalmology
- Modalities
- Biologics (VEGF-C/D ‘trap’ inhibitor)
- Industry
- Biotech
02
Drug pipeline
2 assets1 more asset in the full pipeline.
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Financials
- Market cap
- $4.2B
- Total revenue
- $-3K
- Enterprise value
- $4.4B
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