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Optithera has developed and clinically validated a saliva-based polygenic risk score test that predicts the likelihood of developing kidney, heart, and cerebrovascular complications in patients with type 2 diabetes. The test has been validated in over 20,000 patients from more than 20 countries and shown to improve patient stratification for intensive treatment. Clinical studies demonstrated significant reductions in cardiovascular mortality among high-risk groups identified by the test[4]. The technology is supported by public-private partnerships and funding from Genome Canada.
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