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Preclinical studies demonstrated bone regeneration in animal models. In beagle dogs with induced periodontal disease, 100% (n=3) of animals treated with Ambrilux showed increased bone regeneration at both first and second month post-treatment, compared to only 33% (n=3) of control animals. The company published pivotal manuscript in ACS Applied Materials & Interfaces demonstrating efficacy in multiple animal models with significant reductions in pathogenic biofilm (41%) and metabolic activity (75%).
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