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OrganoTherapeutics

Esch-sur-Alzette, Luxembourgorgano-therapeutics.com ↗

Ownership: Private
Development stage: Preclinical

Overview

OrganoTherapeutics has demonstrated that its proprietary midbrain organoid models recapitulate key pathological features of Parkinson's disease—including dopaminergic neuron loss and alpha-synuclein aggregation. Proof-of-principle studies show that small molecule compounds can rescue these phenotypes in vitro. These results have been published in peer-reviewed journals such as npj Parkinson’s Disease and Science Translational Medicine. No clinical-stage programs reported.

Therapeutic areas: Neurology
Modalities: Small moleculeCell-based disease models (for screening and validation)Recombinant protein (potentially, as part of platform outputs)Biologic (potentially, as part of platform outputs)
Industry: Biotech

Partnerships

Academic collaborations with University of Luxembourg and othersindustry partnerships with European, US, Japanese pharma/biotech companies for joint projects using the organoid platform

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