Company intelligence / Profile preview

Organovo

San Diego, California, United Statesorganovo.com ↗
Ownership
Public · ONVO
Development stage
Other
01

Overview

The company’s lead program, FXR314, demonstrated positive Phase 2 results in MASH with significant reduction in liver fat content and strong safety/tolerability. Additional data presented show improved epithelial barrier function and fibrosis reduction in IBD models. The company also provides advanced preclinical tissue platforms to partners.

Therapeutic areas
GastroenterologyRare DiseasesMetabolic Disorders
Modalities
Small molecules (e.g., FXR agonists)3D bioprinted human tissues for drug discovery and disease modeling
Industry
Biotech
02

Drug pipeline

2 assets

Organovo undisclosed small molecule (Crohn's Disease)

Preclinical

1 more asset in the full pipeline.

03

Partnerships

L’Oreal (for skin tissue testing/cosmetic safety applications)Eli Lilly (purchased the FXR program in February 2025)

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