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ORIC Pharmaceuticals is a clinical-stage biopharmaceutical company dedicated to improving patients' lives by overcoming resistance in cancer. The company's name is an acronym for its mission: Overcoming Resistance In Cancer. ORIC leverages its proprietary resistance platform to develop small molecule therapies that target diverse mechanisms of resistance, including bypass signaling, lineage plasticity, and target mutations. Its lead programs include ORIC-114, a brain-penetrant inhibitor of EGFR and HER2, and ORIC-944, a potent and selective inhibitor of the PRC2 complex. Headquartered in South San Francisco, the company is led by a team of experienced oncology drug hunters and is publicly traded on the Nasdaq.
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