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Original Academic (Shanghai) Biotechnology, also known as Yuanxue Biotech, is a clinical-stage biotechnology company specializing in mRNA-based therapeutics and vaccines. Based in Shanghai, the company leverages a proprietary mRNA-LNP (lipid nanoparticle) delivery platform to develop treatments for infectious diseases and oncology. Its lead program is an mRNA vaccine candidate for COVID-19, which has progressed into clinical trials in China. Original Academic focuses on optimizing mRNA sequence design and delivery systems to improve the stability and efficacy of its candidates. The company is part of a new wave of Chinese biotechs advancing domestic mRNA technology. It aims to provide innovative solutions for global health challenges through its integrated R&D and manufacturing capabilities.
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