Originator

Origin is an AI-driven biotechnology company focused on improving the safety and efficacy of cell and gene therapies through the design of synthetic regulatory DNA. The company's core technology, the Axis foundation model, is trained on massive proprietary datasets of patient-derived cancer single-cell perturbations to design precise "DNA switches" that control therapeutic gene expression. By programming specific gene expression patterns in disease cell-states, Origin aims to create more durable and safer cures for cancer, autoimmune, and neurodegenerative diseases. The company operates a platform model, licensing its unique datasets and AI-designed regulatory elements to pharmaceutical and biotechnology partners.