Company intelligence / Profile preview
OrsoBio
Palo Alto, California, United Statesorsobio.com ↗
- Ownership
- Private
- Development stage
- Preclinical
01
Overview
OrsoBio has completed or is conducting multiple early-stage clinical trials. Its lead programs include a liver-targeted mitochondrial protonophore in Phase 1b for obesity, an ACC2 inhibitor in Phase 2a for insulin resistance/diabetes, and an LXR inverse agonist in Phase 2a for severe hypertriglyceridemia/NASH. Preclinical work is ongoing on a controlled-release protonophore and an ACMSD inhibitor for metabolic/inflammatory disorders. No pivotal efficacy data have been published yet.
- Therapeutic areas
- GastroenterologyEndocrinologyMetabolic Disorders
- Modalities
- Small moleculeProtonophore (a type of small molecule)Inhibitor (small molecule)
- Industry
- Biotech
02
Drug pipeline
7 assets6 more assets in the full pipeline.
03
Partnerships
Eli Lilly and Company (participated as investor)academic collaborations with Yale University (Gerald Shulman)EPFL (Johan Auwerx)Cincinnati Children’s Hospital Medical Center (Takanori Takebe)
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