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Otic Pharma developed a nasally-administered combination drug (OP-02) for otitis media and Eustachian tube dysfunction. The lead program aimed to break the cycle of recurrent/chronic otitis media. At the time of its merger with Tokai Pharmaceuticals in late 2016/early 2017, OP-02 had completed Phase I clinical pharmacodynamic studies with plans to move into Phase II development[3].
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